First-time use of deer antler-derived xenografts for management of severe peri-implantitis with titanium mesh: a case report

BACKGROUND: Increasing dental implant use correlates with rising biological complications. For severe peri-implantitis with significant bone loss, choosing the right sustaining treatment is challenging, as nonsurgical methods often fail. This case details a novel management approach for a male patient with serious peri-implantitis, specifically highlighting the initial use of deer antler xenografts in such a procedure. CASE PRESENTATION: A 42-year-old Iranian male presented with significant challenges, including 8 mm of vertical bone loss and a probing depth of 12 mm around a bone-level Interlock implant (4*11 mm). The novel treatment approach incorporated deer antler xenografts, a titanium mesh to maintain space, and a collagen membrane to encourage guided bone regeneration. Follow-up evaluations, both 2D and 3D, four months postsurgery, revealed complete bone regeneration up to the rough neck of the implant. Furthermore, 24 months of follow-up after the delivery of the crown showed stable results. CONCLUSION: This case illustrates the promising potential of deer antler-derived xenografts in addressing severe peri-implantitis. It emphasizes the necessity for further clinical trials to validate these observations and enhance treatment protocols.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-05-17
DOI
https://doi.org/10.1186/s13256-026-06119-3
Primary Topic
Dental Implant Techniques and Outcomes
Type
article
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article

First-time use of deer antler-derived xenografts for management of severe peri-implantitis with titanium mesh: a case report

Aida Kheiri, Mahdi Kadkhodazadeh
Journal of Medical Case Reports
Dental Implant Techniques and Outcomes
article

First-time use of deer antler-derived xenografts for management of severe peri-implantitis with titanium mesh: a case report

Aida Kheiri, Mahdi Kadkhodazadeh
article en

Abstract

BACKGROUND: Increasing dental implant use correlates with rising biological complications. For severe peri-implantitis with significant bone loss, choosing the right sustaining treatment is challenging, as nonsurgical methods often fail. This case details a novel management approach for a male patient with serious peri-implantitis, specifically highlighting the initial use of deer antler xenografts in such a procedure. CASE PRESENTATION: A 42-year-old Iranian male presented with significant challenges, including 8 mm of vertical bone loss and a probing depth of 12 mm around a bone-level Interlock implant (4*11 mm). The novel treatment approach incorporated deer antler xenografts, a titanium mesh to maintain space, and a collagen membrane to encourage guided bone regeneration. Follow-up evaluations, both 2D and 3D, four months postsurgery, revealed complete bone regeneration up to the rough neck of the implant. Furthermore, 24 months of follow-up after the delivery of the crown showed stable results. CONCLUSION: This case illustrates the promising potential of deer antler-derived xenografts in addressing severe peri-implantitis. It emphasizes the necessity for further clinical trials to validate these observations and enhance treatment protocols.

Journal of Medical Case Reports
Research Institute for Endocrine Sciences (IR), Shahid Beheshti University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 5%
Dental Implant Techniques and Outcomes
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