Clinicoradiological and Histopathological Correlation of Placenta Accreta Spectrum in a Tertiary Care Center

Background: Placenta accreta spectrum (PAS) is an obstetric condition linked to increased maternal morbidity and death. Early detection through clinical assessment and radiological imaging, particularly MRI, may be useful for prenatal diagnosis and surgical planning of selected cases of PAS. However, histological testing is still the gold standard for a conclusive diagnosis. The purpose of this study is to assess the diagnostic concordance of clinical and radiological findings with histology in PAS. Methods: This case series was conducted in a tertiary care center and included 11 cases of histopathologically confirmed PAS. MRI finding, where available, were compared with histopathological analysis of hysterectomy specimens. Descriptive statistics were used to summarize demographics, comorbidities, and diagnostic methods. Results: The average age of the participants was 31.9 years. The prevalent comorbidities were hypothyroidism seen in four (37%) cases, anemia seen in three (27%) cases, and gestational diabetes mellitus (GDM) seen in two (18%) cases. Clinical suspicion of PAS was present in seven of 11 (63.3%) cases, while MRI was performed in five cases and detected PAS in all five (100%) cases. Histopathology confirmed the diagnosis in all cases where clinical suspicion and MRI suggested the diagnosis. Conclusion: In this case series, though clinical evaluation and MRI contributed to antenatal detection of PAS, definitive diagnosis relied on histopathological examination. These findings emphasize the need of a comprehensive diagnostic approach for accurately identifying and managing the PAS.