Trichological disorders in Organ Transplant Recipients - case report and literature review.

Introduction Kidney transplantation is a life-saving procedure for patients with end-stage renal disease. However, long-term immunosuppressive therapy may lead to adverse effects, including hair disorders. Case presentation We present the case of a 31-year-old patient who developed significant alopecia following kidney transplantation and initiation of tacrolimus-based immunosuppression. The psychological impact of hair loss led the patient to consider discontinuing treatment. Dermatological evaluation revealed features of androgenetic alopecia and telogen effluvium. A change in immunosuppression from tacrolimus to cyclosporine A resulted in marked improvement in hair regrowth and overall well-being. To support this observation, we conducted a targeted literature review, identifying four case reports linking alopecia to immunosuppressive therapy in solid organ transplant recipients. Conclusion This case highlights the need for awareness of trichological side effects among transplant clinicians, especially given their potential impact on treatment adherence and patient quality of life. Regular dermatological assessments and individualized management strategies, including the possibility of modifying immunosuppressive regimens, may help reduce these complications.