Association Between Dietary/Supplementary Calcium Intake and Risk of Breast Cancer: A Systematic Review and Meta-Analysis of Cohort Studies

= 35%). In subgroup analyses, inverse associations were observed in both premenopausal and postmenopausal women, across shorter and longer follow-up periods, and in European and American cohorts. Dietary calcium intake, alone or combined with supplements, was associated with a reduced risk, whereas supplemental calcium alone was not. These findings suggest that higher calcium intake, particularly from dietary sources, may modestly reduce breast cancer risk. Further research is needed to confirm causality and clarify mechanisms.

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Publication Details

Journal
Nutrition and Cancer
Published
2026-05-16
DOI
https://doi.org/10.1080/01635581.2026.2668741
Primary Topic
Vitamin D Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between Dietary/Supplementary Calcium Intake and Risk of Breast Cancer: A Systematic Review and Meta-Analysis of Cohort Studies

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Association Between Dietary/Supplementary Calcium Intake and Risk of Breast Cancer: A Systematic Review and Meta-Analysis of Cohort Studies

Omid Asbaghi, Mina Ahmadzadeh, Reyhaneh Rabiee, Mahdi Amirpour, Mehdi Karimi, Nahal Babaeian Amini, Fereshteh Valizadeh, Bagher Larijani, Sayed Hosein Davoodi
article en

Abstract

= 35%). In subgroup analyses, inverse associations were observed in both premenopausal and postmenopausal women, across shorter and longer follow-up periods, and in European and American cohorts. Dietary calcium intake, alone or combined with supplements, was associated with a reduced risk, whereas supplemental calcium alone was not. These findings suggest that higher calcium intake, particularly from dietary sources, may modestly reduce breast cancer risk. Further research is needed to confirm causality and clarify mechanisms.

Nutrition and Cancer
Shahid Sadoughi University of Medical Sciences and Health Services (IR), National Nutrition and Food Technology Research Institute (IR), Shahid Beheshti University of Medical Sciences (IR), Tehran University of Medical Sciences (IR), Bogomolets National Medical University (UA)
Zero hunger
Openalex Percentile: Top 5%
Vitamin D Research Studies
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