Page Kidney Following Ruptured Renal Angiomyolipoma Managed With Selective Embolization: A Case Report

Spontaneous perinephric hematoma (SPH), or Wunderlich syndrome, is a rare but potentially life-threatening emergency most often caused by the rupture of a renal angiomyolipoma (AML). A 60-year-old woman presented with sudden-onset right flank pain and anemia in the absence of trauma. Imaging revealed a large right perinephric hematoma secondary to a ruptured renal AML with giant aneurysms and pseudoaneurysms. Despite the extensive hemorrhage, she remained hemodynamically stable and underwent urgent selective transarterial embolization. Post-embolization imaging confirmed complete hemostasis with preservation of renal parenchyma. A compressive perinephric hematoma resulted in transient Page kidney physiology, which was managed conservatively with blood pressure control. This case illustrates several uncommon features: hemodynamic stability despite massive hemorrhage, concurrent giant aneurysms and pseudoaneurysms, and the development of Page kidney. It underscores the diagnostic utility of contrast-enhanced CT and the increasing role of selective endovascular therapy as a nephron-sparing alternative to nephrectomy. Emerging evidence suggests that vascular complexity within AMLs, particularly giant aneurysms and pseudoaneurysms, may be more predictive of rupture than tumor size alone. Prompt imaging, multidisciplinary coordination, and minimally invasive transarterial embolization can yield excellent outcomes in ruptured AML with complex vascular anatomy. Early angiographic evaluation should be considered in symptomatic or high-risk AMLs, with close monitoring for Page kidney to optimize long-term renal preservation.

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Publication Details

Journal
Cureus
Published
2026-05-16
DOI
https://doi.org/10.7759/cureus.108976
Primary Topic
Tuberous Sclerosis Complex Research
Type
article
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article

Page Kidney Following Ruptured Renal Angiomyolipoma Managed With Selective Embolization: A Case Report

Charbel Ishak, Hanasoge Girishkumar, Katherine Rivero, Rayan Alataa et al.
Cureus
Tuberous Sclerosis Complex Research
article

Page Kidney Following Ruptured Renal Angiomyolipoma Managed With Selective Embolization: A Case Report

Charbel Ishak, Hanasoge Girishkumar, Katherine Rivero, Rayan Alataa, Kriti Gupta
article en

Abstract

Spontaneous perinephric hematoma (SPH), or Wunderlich syndrome, is a rare but potentially life-threatening emergency most often caused by the rupture of a renal angiomyolipoma (AML). A 60-year-old woman presented with sudden-onset right flank pain and anemia in the absence of trauma. Imaging revealed a large right perinephric hematoma secondary to a ruptured renal AML with giant aneurysms and pseudoaneurysms. Despite the extensive hemorrhage, she remained hemodynamically stable and underwent urgent selective transarterial embolization. Post-embolization imaging confirmed complete hemostasis with preservation of renal parenchyma. A compressive perinephric hematoma resulted in transient Page kidney physiology, which was managed conservatively with blood pressure control. This case illustrates several uncommon features: hemodynamic stability despite massive hemorrhage, concurrent giant aneurysms and pseudoaneurysms, and the development of Page kidney. It underscores the diagnostic utility of contrast-enhanced CT and the increasing role of selective endovascular therapy as a nephron-sparing alternative to nephrectomy. Emerging evidence suggests that vascular complexity within AMLs, particularly giant aneurysms and pseudoaneurysms, may be more predictive of rupture than tumor size alone. Prompt imaging, multidisciplinary coordination, and minimally invasive transarterial embolization can yield excellent outcomes in ruptured AML with complex vascular anatomy. Early angiographic evaluation should be considered in symptomatic or high-risk AMLs, with close monitoring for Page kidney to optimize long-term renal preservation.

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Tuberous Sclerosis Complex Research
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