Third-Degree Burn Management in Surgery

Third-degree (full-thickness) burns are severe injuries characterized by complete destruction of the epidermis and dermis, eliminating the intrinsic regenerative capacity of the skin and necessitating surgical intervention for definitive management. Contemporary treatment is based on early resuscitation, prompt excision of necrotic tissue, definitive wound coverage, and structured long-term rehabilitation. Early excision and split-thickness skin grafting (STSG) remain the gold standard, significantly reducing mortality, infection, and hospital stay. Advances in dermal substitutes and bioengineered skin have expanded reconstructive options in extensive burns. A multidisciplinary approach is essential to optimize survival, functional outcomes, and long-term quality of life.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-05-16
DOI
https://doi.org/10.5281/zenodo.20227668
Primary Topic
Wound Healing and Treatments
Type
article
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article

Third-Degree Burn Management in Surgery

Sergio Morales Acosta, Karla Daniela Martínez García, Bryan Rodríguez Elizalde, Paola Itzel Romo Correa
Zenodo (CERN European Organization for Nuclear Research)
Wound Healing and Treatments
article

Third-Degree Burn Management in Surgery

Sergio Morales Acosta, Karla Daniela Martínez García, Bryan Rodríguez Elizalde, Paola Itzel Romo Correa
article en

Abstract

Third-degree (full-thickness) burns are severe injuries characterized by complete destruction of the epidermis and dermis, eliminating the intrinsic regenerative capacity of the skin and necessitating surgical intervention for definitive management. Contemporary treatment is based on early resuscitation, prompt excision of necrotic tissue, definitive wound coverage, and structured long-term rehabilitation. Early excision and split-thickness skin grafting (STSG) remain the gold standard, significantly reducing mortality, infection, and hospital stay. Advances in dermal substitutes and bioengineered skin have expanded reconstructive options in extensive burns. A multidisciplinary approach is essential to optimize survival, functional outcomes, and long-term quality of life.

Zenodo (CERN European Organization for Nuclear Research)
Universidad Autónoma de Guadalajara (MX), Universidad de Guadalajara (MX), Universidad Vasco de Quiroga (MX), Tominaga hospital (JP)
Good health and well-being
Openalex Percentile: Top 6%
Wound Healing and Treatments
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