Metalens Enables Parallel Chromatic Confocal Imaging over a Millimeter-Scale Depth Range with an Axial Space–Bandwidth Product of 68
Confocal microscopy provides optical sectioning and micrometer-scale resolution but remains constrained by mechanical axial scanning and bulky optics. Leveraging the intrinsic chromatic dispersion of a custom-designed metalens, we demonstrate parallel confocal depth imaging over a 1.3 mm axial range within a 200 nm visible bandwidth by encoding wavelengths into different axial positions to eliminate mechanical axial scanning, which yields an axial space-bandwidth product (ASBP) of ≈68. A single-mode fiber functions simultaneously as an illumination/collection probe and confocal pinhole, forming a compact design. The system achieves an axial resolution of 11.4 μm (axial sensitivity of 0.15 μm) and a lateral resolution of 2.19 μm near the optimal wavelength of 530 nm. The parallel confocal imaging capability across an extended depth is further validated by depth-resolved imaging and surface profile measurement. This compact, label-free platform underscores the potential of meta-optical chromatic confocal imaging for large-depth, high-resolution microscopic applications.
Authors
- Z B Liu
- Xingjie Ni (ORCID: https://orcid.org/0000-0001-7405-5678)
- Bofeng Liu (ORCID: https://orcid.org/0000-0002-3851-2939)
- Y. F. Lin
- Tunan Xia (ORCID: https://orcid.org/0009-0009-8888-4114)
- Jinkai Yang (ORCID: https://orcid.org/0009-0004-7324-7087)
- Linghan Zhao
- Md Tarek Rahman
- Guoyu Ding
Institutions
- Pennsylvania State University (US)
Publication Details
- Journal
- Nano Letters
- Published
- 2026-05-16
- DOI
- https://doi.org/10.1021/acs.nanolett.6c01339
- Primary Topic
- Advanced Fluorescence Microscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Biomedical Imaging and Bioengineering