From the NOD Mouse to Patients: Type 1 Conventional Dendritic Cells as a Therapeutic Target in Type 1 Diabetes.

T cells. Notably, inhibiting this cross-presentation has been shown to prevent T1D in NOD mice. Therefore, as we strive to find strategies to inhibit T1D onset and progression, insights from NOD mice provide important guidance for understanding human T1D and for developing targeted immunotherapies.