Genital ulcer associated with an uncommon viral infection

We present a case of adult T-cell leukemia/lymphoma that manifested as localized necrotic lesions on the penis in an octogenarian patient born in Iran. A diagnosis of scleritis and panuveitis of the right eye was made oncomitantly. Histopathological examination revealed an angiocentric and necrotic atypical lymphocytic proliferation with an immunohistochemical profile positive for CD30. This unique presentation highlights the importance for dermatologists of being familiar with the diverse clinical and epidemiological characteristics of HTLV-1 infection.

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Publication Details

Journal
Clinical and Experimental Dermatology
Published
2026-05-11
DOI
https://doi.org/10.1093/ced/llag203
Primary Topic
T-cell and Retrovirus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Genital ulcer associated with an uncommon viral infection

I. Matei, N. Dupin, Nathalie Franck, A. Carlotti et al.
Clinical and Experimental Dermatology
T-cell and Retrovirus Studies
article

Genital ulcer associated with an uncommon viral infection

I. Matei, N. Dupin, Nathalie Franck, A. Carlotti, Pierre Sohier
article en

Abstract

We present a case of adult T-cell leukemia/lymphoma that manifested as localized necrotic lesions on the penis in an octogenarian patient born in Iran. A diagnosis of scleritis and panuveitis of the right eye was made oncomitantly. Histopathological examination revealed an angiocentric and necrotic atypical lymphocytic proliferation with an immunohistochemical profile positive for CD30. This unique presentation highlights the importance for dermatologists of being familiar with the diverse clinical and epidemiological characteristics of HTLV-1 infection.

Clinical and Experimental Dermatology
Université Paris Cité (FR), Hôpital Cochin (FR), Assistance Publique – Hôpitaux de Paris (FR)
Good health and well-being
Openalex Percentile: Top 7%
T-cell and Retrovirus Studies
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