PAM1 regulates meiosis by coupling RNA processing to the chromosome axis
controls only a subset of meiotic genes and processes, indicating that several programs directing transcriptome architecture collectively regulate meiosis. RNA-binding proteins have been found to control meiosis progression in fungi and animals, and it is now shown to be also the case in plants. Interestingly, these proteins all exhibit distinct modes of action and evolutionary origins, presenting a remarkable case of convergent evolution. Uncovering mechanisms controlling meiosis progression should enable engineering meiosis to benefit crop improvement efforts.
Authors
- Robert Bukowski
- Robert Meeley (ORCID: https://orcid.org/0000-0002-4496-1888)
- Inna Golubovskaya
- Ju‐Kyung Yu
- Wojciech P. Pawlowski
- Otto Hudecz (ORCID: https://orcid.org/0000-0003-1099-0741)
- Qian Du (ORCID: https://orcid.org/0000-0001-7438-9838)
- Elisabeth Roitinger (ORCID: https://orcid.org/0000-0002-3405-7801)
- Rachel Wang (ORCID: https://orcid.org/0000-0002-1046-3012)
- Minghui Wang (ORCID: https://orcid.org/0000-0002-0928-4180)
- Choon-Lin Tiang (ORCID: https://orcid.org/0009-0006-9204-8790)
- Paul Altendorf
- Moira J. Sheehan (ORCID: https://orcid.org/0000-0002-3400-2165)
- Clint Ko
Institutions
- Institute of Molecular Biotechnology (AT)
- Cornell University (US)
- Pioneer Hi-Bred (US)
- Institute of Plant and Microbial Biology, Academia Sinica (TW)
- Institute of Molecular Biology and Biotechnology (BG)
- Syngenta (China) (CN)
Publication Details
- Journal
- Proceedings of the National Academy of Sciences
- Published
- 2026-05-13
- DOI
- https://doi.org/10.1073/pnas.2535316123
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Agriculture