Effect of remote ischemic conditioning on prognosis and serum Maresin 1 levels in patients with acute ischemic stroke

OBJECTIVE: To investigate the effects of remote ischemic conditioning (RIC) on clinical outcomes and serum Maresin 1 (MaR1) levels in patients with mild‑to‑moderate acute ischemic stroke (AIS) who did not undergo vascular recanalization. METHODS: = 54, conventional treatment alone). Modified Rankin Scale (mRS), NIH Stroke Scale (NIHSS) scores, and MaR1 levels were assessed. RESULTS: < 0.001). CONCLUSION: In AIS patients not receiving vascular recanalization, RIC therapy significantly improves neurological recovery and reduces disability. This neuroprotective effect may be mediated in part by upregulation of MaR1.

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Publication Details

Journal
Neurological Research
Published
2026-05-12
DOI
https://doi.org/10.1080/01616412.2026.2666882
Primary Topic
Cardiac Ischemia and Reperfusion
Type
article
Field-Weighted Citation Impact
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article

Effect of remote ischemic conditioning on prognosis and serum Maresin 1 levels in patients with acute ischemic stroke

Jixia Wu, Xinyu Qiao, Yingying LIN, Wei Liu et al.
Neurological Research
Cardiac Ischemia and Reperfusion
article

Effect of remote ischemic conditioning on prognosis and serum Maresin 1 levels in patients with acute ischemic stroke

Jixia Wu, Xinyu Qiao, Yingying LIN, Wei Liu, Shanshan Wang, Yadi Sun
article en

Abstract

OBJECTIVE: To investigate the effects of remote ischemic conditioning (RIC) on clinical outcomes and serum Maresin 1 (MaR1) levels in patients with mild‑to‑moderate acute ischemic stroke (AIS) who did not undergo vascular recanalization. METHODS: = 54, conventional treatment alone). Modified Rankin Scale (mRS), NIH Stroke Scale (NIHSS) scores, and MaR1 levels were assessed. RESULTS: < 0.001). CONCLUSION: In AIS patients not receiving vascular recanalization, RIC therapy significantly improves neurological recovery and reduces disability. This neuroprotective effect may be mediated in part by upregulation of MaR1.

Neurological Research
Shanghai Tenth People's Hospital (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Good health and well-being
Openalex Percentile: Top 5%
Cardiac Ischemia and Reperfusion
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