Effects of different caffeine doses on fat oxidation and cardiovascular response during exercise at FATmax in overweight/obese female college students

PURPOSE: This study examined the acute effects of different caffeine doses on fat oxidation and cardiovascular responses at rest and during exercise at the intensity of maximal fat oxidation (FATmax) in overweight/obese sedentary female college students. METHODS: < 0.05. RESULTS: < 0.05). CONCLUSION: Acute caffeine intake at 3 and 5 mg/kg enhanced fat oxidation during FATmax exercise in sedentary overweight/obese females, whereas 9 mg/kg provided no additional metabolic benefit. However, the 5 mg/kg dose was associated with increased cardiovascular strain, which was not observed with the 3 mg/kg. Therefore, a dose of 3 mg/kg appears to offer an optimal balance between stimulating fat oxidation and maintaining cardiovascular safety in this population during acute exercise.

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Publication Details

Journal
Journal of the International Society of Sports Nutrition
Published
2026-05-12
DOI
https://doi.org/10.1080/15502783.2026.2670558
Primary Topic
Coffee research and impacts
Type
article
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article

Effects of different caffeine doses on fat oxidation and cardiovascular response during exercise at FATmax in overweight/obese female college students

Tianou Zhang, Zhen Lyu, Wenying Huang, Zhigang Gong et al.
Journal of the International Society of Sports Nutrition
Coffee research and impacts
article

Effects of different caffeine doses on fat oxidation and cardiovascular response during exercise at FATmax in overweight/obese female college students

Tianou Zhang, Zhen Lyu, Wenying Huang, Zhigang Gong, Shihong Yu
article en

Abstract

PURPOSE: This study examined the acute effects of different caffeine doses on fat oxidation and cardiovascular responses at rest and during exercise at the intensity of maximal fat oxidation (FATmax) in overweight/obese sedentary female college students. METHODS: < 0.05. RESULTS: < 0.05). CONCLUSION: Acute caffeine intake at 3 and 5 mg/kg enhanced fat oxidation during FATmax exercise in sedentary overweight/obese females, whereas 9 mg/kg provided no additional metabolic benefit. However, the 5 mg/kg dose was associated with increased cardiovascular strain, which was not observed with the 3 mg/kg. Therefore, a dose of 3 mg/kg appears to offer an optimal balance between stimulating fat oxidation and maintaining cardiovascular safety in this population during acute exercise.

Journal of the International Society of Sports NutritionVol. 23(1)
Center for Health, Exercise and Sport Sciences (RS), Nutrition Sciences (Belgium) (BE), Crest Middle School (US), Jiangxi Normal University (CN)
Zero hunger
Openalex Percentile: Top 6%
Coffee research and impacts
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