Sonosensitized Hemoglobin Nanoparticles for Ultrasound-Triggered NO Gas Therapy of Periodontitis
studies confirm that PH-SNO/US alleviates gingival inflammation, suppresses osteoclast activity, preserves alveolar bone, and promotes tissue repair with excellent biocompatibility, providing a safe, noninvasive, and translatable nonantibiotic therapeutic strategy for periodontitis.
Authors
- Fengli Wu (ORCID: https://orcid.org/0000-0002-2748-5330)
- Zhaohui Tang (ORCID: https://orcid.org/0000-0003-4726-4305)
- Shujun Dong (ORCID: https://orcid.org/0009-0005-8584-1013)
- Xinchao Wang
Institutions
- Jilin University (CN)
- Chinese Academy of Sciences (CN)
- Changchun Institute of Applied Chemistry (CN)
- First Hospital of Jilin University (CN)
- Jilin Medical University (CN)
Publication Details
- Journal
- Nano Letters
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1021/acs.nanolett.6c01324
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- People's Government of Jilin Province