Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides for Safe and Effective mRNA Delivery <i>In Vitro</i> and <i>In Vivo</i>

Authors

T Stephanie Tran (ORCID: https://orcid.org/0009-0005-9297-4623)
Trisha I. Valerio (ORCID: https://orcid.org/0000-0002-3523-4937)
Anand Annan
Dixy E. Green (ORCID: https://orcid.org/0000-0002-6237-0889)
Paul L. DeAngelis (ORCID: https://orcid.org/0000-0002-8843-1344)
Stefan Wilhelm (ORCID: https://orcid.org/0000-0003-2167-6221)
W Chen
Yuanhong Sun (ORCID: https://orcid.org/0009-0001-4174-8897)
Yuxin He (ORCID: https://orcid.org/0009-0007-6782-6308)
Kar‐Ming Fung
Rameswari Velayutham
Kaili Liu
Mobina Mohammadnejad
James Bowman
Lin Wang (ORCID: https://orcid.org/0000-0003-4636-8225)
Samantha D. Ricketts

Institutions

Institute for Biomedical Engineering (CH)
Division of Materials Science and Engineering (AU)
OU Health Stephenson Cancer Center
University of Oklahoma Health Sciences Center (US)
University of Oklahoma (US)

Publication Details

Journal: ACS Applied Materials & Interfaces
Published: 2026-05-12
DOI: https://doi.org/10.1021/acsami.6c05213
Primary Topic: RNA Interference and Gene Delivery
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Oklahoma Center for Adult Stem Cell Research
National Science Foundation
Presbyterian Health Foundation
University of Oklahoma
National Institutes of Health

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article

Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides for Safe and Effective mRNA Delivery In Vitro and In Vivo

T Stephanie Tran, Trisha I. Valerio, Anand Annan, Dixy E. Green et al.

May 12, 2026

ACS Applied Materials & Interfaces

RNA Interference and Gene Delivery

article

Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides for Safe and Effective mRNA Delivery In Vitro and In Vivo

T Stephanie Tran, Trisha I. Valerio, Anand Annan, Dixy E. Green, Paul L. DeAngelis, Stefan Wilhelm, W Chen, Yuanhong Sun, Yuxin He, Kar‐Ming Fung, Rameswari Velayutham, Kaili Liu, Mobina Mohammadnejad, James Bowman, Lin Wang, Samantha D. Ricketts

May 12, 2026article en

Abstract

No abstract available for this paper.

ACS Applied Materials & Interfaces

Institute for Biomedical Engineering (CH), Division of Materials Science and Engineering (AU), OU Health Stephenson Cancer Center, University of Oklahoma Health Sciences Center (US), University of Oklahoma (US)

Oklahoma Center for Adult Stem Cell Research, National Science Foundation, Presbyterian Health Foundation, University of Oklahoma, National Institutes of Health

Industry, innovation and infrastructure

Openalex Percentile: Top 7%

RNA Interference and Gene Delivery

DOI Open Access PDF OpenAlex

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Lipid Nanoparticle Surface Engineering with Heparosan Polysaccharides for Safe and Effective mRNA Delivery <i>In Vitro</i> and <i>In Vivo</i> — T Stephanie Tran, Trisha I. Valerio, et al. · ACS Applied Materials & Interfaces (2026) | TGRS Research Map | TGRS