Benefits of Electronic Symptom Monitoring During Cancer Treatment by Age, Sex, Race, and Education (Alliance AFT-39)
PURPOSE: Remote symptom monitoring using patient-reported outcomes (PROs) has been shown to improve symptom control and physical function among patients with advanced cancer. However, it is unclear whether these benefits are similar across demographic groups. This exploratory analysis of the PRO-TECT trial examined whether the effects of electronic symptom monitoring varied by race, age, sex, and educational attainment. METHODS: >high school). RESULTS: = .02) versus UC. Benefits were most pronounced among younger, female, Black, and less educated participants. Black participants in the PRO arm were more likely to report that symptom reporting made them feel more in control of their care compared with White participants. CONCLUSION: Electronic symptom monitoring improved quality-of-life outcomes overall, including among groups who have historically experienced higher symptom burden or barriers to communication. Remote PRO systems may represent an equitable strategy to enhance cancer care delivery.
Authors
- Brenda Ginos
- Patricia A. Spears (ORCID: https://orcid.org/0000-0003-1167-0387)
- Gina L. Mazza (ORCID: https://orcid.org/0000-0002-5305-6193)
- Cindy Geoghegan (ORCID: https://orcid.org/0000-0003-0992-3728)
- D Cella
- Anna Weiss
- Yashasvini Sampathkumar (ORCID: https://orcid.org/0009-0007-2120-2620)
- Barbara Given
- V. S. Blinder
- Antonia V. Bennet (ORCID: https://orcid.org/0000-0002-8968-4511)
- Ethan Basch (ORCID: https://orcid.org/0000-0003-3813-9318)
- Deborah Schrag (ORCID: https://orcid.org/0000-0002-4334-5717)
- Bryce B. Reeve (ORCID: https://orcid.org/0000-0002-6709-8714)
- Amylou C. Dueck (ORCID: https://orcid.org/0000-0002-9912-1085)
- Anna P. Wolf
- Gita Thanarajasingam (ORCID: https://orcid.org/0000-0003-2144-5415)
- Philip M. Carr
- Claire Snyder (ORCID: https://orcid.org/0000-0001-8952-4561)
- Angela M. Stover (ORCID: https://orcid.org/0000-0003-0983-686X)
- Allison M. Deal (ORCID: https://orcid.org/0000-0003-3526-3938)
- Dylan M. Zylla (ORCID: https://orcid.org/0000-0003-1726-3715)
- Mattias Jonsson (ORCID: https://orcid.org/0000-0002-0846-3742)
- Jennifer Jansen (ORCID: https://orcid.org/0000-0001-6993-3069)
- Lauren Rogak (ORCID: https://orcid.org/0009-0009-9430-2256)
Institutions
- Northwestern University (US)
- University of North Carolina at Chapel Hill (US)
- Memorial Sloan Kettering Cancer Center (US)
- Johns Hopkins University (US)
- Duke University (US)
- Alliance for Clinical Trials in Oncology (US)
- University of Rochester Medical Center (US)
- Park Nicollet Health Services (US)
- Park Nicollet Clinic (US)
- Mayo Clinic in Arizona (US)
- UNC Lineberger Comprehensive Cancer Center
- Michigan State University (US)
- National Patient Safety Foundation (US)
Publication Details
- Journal
- JCO Oncology Practice
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1200/op-26-00015
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 0.00