Disseminated cystic echinococcosis presenting as orbital swelling in a child — case report and literature review

BACKGROUND: Cystic echinococcosis (CE) is a parasitic disease that commonly affects the liver and lungs. Orbital involvement is an unusual presentation, particularly in non-endemic areas, and poses diagnostic and therapeutic challenges. CASE PRESENTATION AND LITERATURE REVIEW: We report the case of a five-year-old girl from Syria who presented with orbital swelling and was ultimately diagnosed with disseminated CE. The diagnosis was delayed, and management was complicated by intraoperative cyst rupture and spillage. Surgical resection combined with antiparasitic therapy resulted in regression of the cysts. A scoping review of the literature identified 15 reports of orbital CE in children, most of them from endemic countries. CONCLUSION: CE should be considered in children presenting with cystic lesions and a history of migration from endemic areas. Early involvement of a CE reference center is essential to prevent complications and to optimize management.

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Publication Details

Journal
Infection
Published
2026-05-13
DOI
https://doi.org/10.1007/s15010-026-02743-9
Primary Topic
Parasitic infections in humans and animals
Type
article
Field-Weighted Citation Impact
0.00

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article

Disseminated cystic echinococcosis presenting as orbital swelling in a child — case report and literature review

Hendrik Rosewich, Robert Rottscholl, Sabine Bélard, Mariya Gosheva et al.
Infection
Parasitic infections in humans and animals
article

Disseminated cystic echinococcosis presenting as orbital swelling in a child — case report and literature review

Hendrik Rosewich, Robert Rottscholl, Sabine Bélard, Mariya Gosheva, Marija Stojković, Jonathan Remppis
article en

Abstract

BACKGROUND: Cystic echinococcosis (CE) is a parasitic disease that commonly affects the liver and lungs. Orbital involvement is an unusual presentation, particularly in non-endemic areas, and poses diagnostic and therapeutic challenges. CASE PRESENTATION AND LITERATURE REVIEW: We report the case of a five-year-old girl from Syria who presented with orbital swelling and was ultimately diagnosed with disseminated CE. The diagnosis was delayed, and management was complicated by intraoperative cyst rupture and spillage. Surgical resection combined with antiparasitic therapy resulted in regression of the cysts. A scoping review of the literature identified 15 reports of orbital CE in children, most of them from endemic countries. CONCLUSION: CE should be considered in children presenting with cystic lesions and a history of migration from endemic areas. Early involvement of a CE reference center is essential to prevent complications and to optimize management.

Infection
Heidelberg University (DE), University Hospital Heidelberg (DE), German Center for Infection Research (DE), Universitätsmedizin Göttingen (DE), University Children's Hospital Tübingen (DE), German Centre for Cardiovascular Research (DE), Hertie Institute for Clinical Brain Research (DE), University of Göttingen (DE), University of Tübingen (DE)
Deutsches Zentrum für Infektionsforschung, Universitätsklinikum Tübingen
Gender equality
Openalex Percentile: Top 6%
Parasitic infections in humans and animals
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