Design and validation of renal stone detection using multi-architecture feature extraction with deep sequential learning model on axial computed tomography images

Kidney stone disease is a significant public health threat, with its prevalence escalating due to evolving dietary habits, rising rates of obesity, other medical conditions, and the use of certain supplements. A kidney stone, otherwise known as a renal calculus, is a solid mass of crystallized minerals that aggregates within the kidneys. The proper identification of this renal condition is vital because it represents a serious health issue that requires accurate detection for effective treatment. Imaging techniques play a vital role in diagnosing kidney diseases, including kidney stones. Computed tomography (CT) is among the imaging techniques utilized to detect kidney stones by medical specialists. CT scans provide information on a stone's specific location and size, allowing for an estimation of the chances for natural expulsion, thus potentially avoiding the need for surgical procedures. Deep learning (DL) models are progressively renowned as a robust tool for disease diagnosis in the biomedical domain. This study presents a Feature Integration and Sequential Attention Framework for Kidney Stone Detection (FISAF-KSD) approach. The primary goal of this work is to develop a reliable and efficient system that can accurately identify kidney stones from CT images. To achieve this, the FISAF-KSD approach initially performs image pre-processing and augmentation to improve input image quality and prepare CT images for further analysis. Following this, feature extraction is carried out through a fusion of three DL models, such as EfficientNetV2L, InceptionV3, and ResNet-101, to capture the key features of kidney stones at both detailed and broad levels. Finally, a bidirectional gated recurrent unit network (BiGRU) with an attention mechanism (AM) is employed to classify renal stones effectively. The performance analysis of the FISAF-KSD methodology is thoroughly examined under the Axial CT imaging dataset. The FISAF-KSD methodology accomplished [Formula: see text] of 98.75%, [Formula: see text] of 98.76%, [Formula: see text] of 98.75%, [Formula: see text] of 98.75%, and [Formula: see text] of 98.75%. The results indicate that the FISAF-KSD methodology performed better compared to existing approaches.

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Publication Details

Journal
Scientific Reports
Published
2026-05-12
DOI
https://doi.org/10.1038/s41598-026-45383-7
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
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article

Design and validation of renal stone detection using multi-architecture feature extraction with deep sequential learning model on axial computed tomography images

Saad Alowayyed, Turke Althobaiti, Sahar Mansour, Lama Abdulrahman Alharkan et al.
Scientific Reports
Kidney Stones and Urolithiasis Treatments
article

Design and validation of renal stone detection using multi-architecture feature extraction with deep sequential learning model on axial computed tomography images

Saad Alowayyed, Turke Althobaiti, Sahar Mansour, Lama Abdulrahman Alharkan, Majdy M. Eltahir, Alanoud Subahi, Sultan Almutairi, Mutasim Al Sadig
article en

Abstract

Kidney stone disease is a significant public health threat, with its prevalence escalating due to evolving dietary habits, rising rates of obesity, other medical conditions, and the use of certain supplements. A kidney stone, otherwise known as a renal calculus, is a solid mass of crystallized minerals that aggregates within the kidneys. The proper identification of this renal condition is vital because it represents a serious health issue that requires accurate detection for effective treatment. Imaging techniques play a vital role in diagnosing kidney diseases, including kidney stones. Computed tomography (CT) is among the imaging techniques utilized to detect kidney stones by medical specialists. CT scans provide information on a stone's specific location and size, allowing for an estimation of the chances for natural expulsion, thus potentially avoiding the need for surgical procedures. Deep learning (DL) models are progressively renowned as a robust tool for disease diagnosis in the biomedical domain. This study presents a Feature Integration and Sequential Attention Framework for Kidney Stone Detection (FISAF-KSD) approach. The primary goal of this work is to develop a reliable and efficient system that can accurately identify kidney stones from CT images. To achieve this, the FISAF-KSD approach initially performs image pre-processing and augmentation to improve input image quality and prepare CT images for further analysis. Following this, feature extraction is carried out through a fusion of three DL models, such as EfficientNetV2L, InceptionV3, and ResNet-101, to capture the key features of kidney stones at both detailed and broad levels. Finally, a bidirectional gated recurrent unit network (BiGRU) with an attention mechanism (AM) is employed to classify renal stones effectively. The performance analysis of the FISAF-KSD methodology is thoroughly examined under the Axial CT imaging dataset. The FISAF-KSD methodology accomplished [Formula: see text] of 98.75%, [Formula: see text] of 98.76%, [Formula: see text] of 98.75%, [Formula: see text] of 98.75%, and [Formula: see text] of 98.75%. The results indicate that the FISAF-KSD methodology performed better compared to existing approaches.

Scientific Reports
Princess Nourah bint Abdulrahman University (SA), Northern Border University (SA), King Abdulaziz City for Science and Technology (SA), King Abdulaziz University (SA), Majmaah University (SA), Shaqra University (SA), King Saud University (SA), King Khalid University (SA)
Good health and well-being
Openalex Percentile: Top 5%
Kidney Stones and Urolithiasis Treatments
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