PolyGraph – Flexible, Biocompatible & Electrically Optimized Graphene‐Polymer Composites for Next‐Generation Neural Interfaces
for a 100 ms pulse), enhanced by NaOH surface roughening and AuPd coating. Leveraging their processability, PolyGraph composites are fabricated into flexible, individually isolated microneedle electrode arrays with biomimetic soft hyaluronic acid backings. These arrays demonstrate bidirectional neural interfacing capabilities, enabling both the delivery of controlled stimulation pulses in physiological buffer and high-resolution neuronal recording in murine brain slices, with machine learning-based event classification. Together, these advances establish PolyGraph as an optimal material platform for next-generation brain-computer interfaces and soft bioelectronic devices.
Authors
- Jonathan N. Coleman (ORCID: https://orcid.org/0000-0001-9659-9721)
- Cian O’Connor (ORCID: https://orcid.org/0000-0001-9792-2746)
- Omar Mamad (ORCID: https://orcid.org/0000-0002-4517-3381)
- Jack Maughan (ORCID: https://orcid.org/0000-0003-0716-2697)
- Ian Woods (ORCID: https://orcid.org/0000-0002-7889-1590)
- Eoin Caffrey (ORCID: https://orcid.org/0000-0002-0174-383X)
- Fergal J. O’Brien (ORCID: https://orcid.org/0000-0003-2030-8005)
- Pablo Quintana-Sarti
- Tian Carey (ORCID: https://orcid.org/0000-0001-8697-9421)
- Adrian Dervan (ORCID: https://orcid.org/0000-0001-9201-276X)
- Alejandro López Valdés (ORCID: https://orcid.org/0000-0002-5568-9808)
- Jose M. Munuera (ORCID: https://orcid.org/0000-0002-8176-4795)
- Maeve A. Caldwell (ORCID: https://orcid.org/0000-0001-7442-711X)
Institutions
- Royal College of Surgeons in Ireland (IE)
- Trinity College Dublin (IE)
- Instituto Nacional del Carbón (ES)
- Advanced Materials and BioEngineering Research (IE)
Publication Details
- Journal
- Advanced Healthcare Materials
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1002/adhm.202505076
- Primary Topic
- Neuroscience and Neural Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00