Temporal genetic changes in human bocavirus 1 in Fukushima, Japan, from 2018 to 2024
Clinically circulating HBoV1 undergoes temporal genetic change, with group differentiation determined primarily by VP genes and uniquely by ORFx at the amino acid level. These findings suggest a potential biological role for ORFx in the HBoV1 life cycle. Understanding these temporal genetic shifts is important for enhancing the accuracy of molecular surveillance tools, particularly for distinguishing genetically diverse HBoV1 strains.
Authors
- Hisao Okabe (ORCID: https://orcid.org/0000-0003-2416-3288)
- Masatoshi Kakizaki (ORCID: https://orcid.org/0000-0002-9388-8402)
- Hayato Go (ORCID: https://orcid.org/0000-0002-0138-6676)
- Satoko Sugimoto (ORCID: https://orcid.org/0009-0002-5042-1543)
- Yohei Kume (ORCID: https://orcid.org/0000-0003-2985-1282)
- Takashi Okura (ORCID: https://orcid.org/0000-0002-6019-958X)
- Sakurako Norito
- Miyuki Kawase
- Shigeo Suzuki
- Hiroko Sakuma (ORCID: https://orcid.org/0009-0006-0069-5553)
- Koichi Hashimoto
- Mitsuaki Hosoya
- Tatsuya Shirai
- Kazuya Shirato (ORCID: https://orcid.org/0000-0002-3375-9799)
Institutions
- Fukushima Medical University (JP)
- Kyorin University (JP)
- National Institute of Infectious Diseases (JP)
- Star General Hospital (JP)
- Fukushima Medical University Hospital (JP)
Publication Details
- Journal
- Journal of Medical Microbiology
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1099/jmm.0.002165
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development