Peroxisome calcium uptake is dependent on ER-peroxisome membrane contact
uptake. Further, we identify the ACBD5-dependent peroxisome-ER contact site as the major factor restricting peroxisome motility within the cell. Microtubules and SOCE stimulation exert smaller and independent effects on peroxisome motility. This work expands the range of known functions of the peroxisome-ER contact site.
Authors
- Sven Thoms (ORCID: https://orcid.org/0000-0003-3018-6363)
- Julia Kalinowski (ORCID: https://orcid.org/0000-0002-3364-1803)
- Alexander Lütkemeyer (ORCID: https://orcid.org/0009-0007-0959-1416)
- Yelena Hartmann (ORCID: https://orcid.org/0000-0002-6749-7555)
Institutions
- Bielefeld University (DE)
- Hochschule Bielefeld (DE)
- Deutsches Herzzentrum München (DE)
Publication Details
- Journal
- Cellular and Molecular Life Sciences
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1007/s00018-026-06191-4
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universität Bielefeld