Structure-Based Design of UVRAG-BAX Binding Interface-Targeting Compound Induces Apoptosis and ROS in Breast Cancer Cells

]chromen-3-yl)acetyl]-4-phenylpiperidine-4-carboxylic acid (ZINC000002107582) is a promising lead compound that targets the UVRAG interaction interface and exerts potent anticancer effects in breast cancer cells.

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Publication Details

Journal
Biochemistry
Published
2026-05-12
DOI
https://doi.org/10.1021/acs.biochem.6c00269
Primary Topic
Photochromic and Fluorescence Chemistry
Type
article
Field-Weighted Citation Impact
0.00
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article

Structure-Based Design of UVRAG-BAX Binding Interface-Targeting Compound Induces Apoptosis and ROS in Breast Cancer Cells

Raj Bahadur Singh, Shivank Kumar, Vikash Kumar Dubey
Biochemistry
Photochromic and Fluorescence Chemistry
article

Structure-Based Design of UVRAG-BAX Binding Interface-Targeting Compound Induces Apoptosis and ROS in Breast Cancer Cells

Raj Bahadur Singh, Shivank Kumar, Vikash Kumar Dubey
article en

Abstract

]chromen-3-yl)acetyl]-4-phenylpiperidine-4-carboxylic acid (ZINC000002107582) is a promising lead compound that targets the UVRAG interaction interface and exerts potent anticancer effects in breast cancer cells.

Biochemistry
Indian Institute of Technology BHU (IN)
Good health and well-being
Openalex Percentile: Top 10%
Photochromic and Fluorescence Chemistry
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Structure-Based Design of UVRAG-BAX Binding Interface-Targeting Compound Induces Apoptosis and ROS in Breast Cancer Cells — Raj Bahadur Singh, Shivank Kumar, et al. · Biochemistry (2026) | TGRS Research Map | TGRS