Researchers urge slow tapers in deprescribing

Deprescribing antidepressants for children and adolescents should be guided by data as well as observation of the ­patient's relapse and withdrawal symptoms, according to a new study. Clinicians should also consider the pharmacokinetic and pharmacodynamic properties of medications, including when and how to initiate deprescribing, the researchers add. These considerations are critically important to the clinician‐family‐patient relationship.

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Publication Details

Journal
The Brown University Child and Adolescent Behavior Letter
Published
2026-05-12
DOI
https://doi.org/10.1002/cbl.30954
Primary Topic
Treatment of Major Depression
Type
article
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Researchers urge slow tapers in deprescribing

Alison Knopf
The Brown University Child and Adolescent Behavior Letter
Treatment of Major Depression
article

Researchers urge slow tapers in deprescribing

Alison Knopf
article en

Abstract

Deprescribing antidepressants for children and adolescents should be guided by data as well as observation of the ­patient's relapse and withdrawal symptoms, according to a new study. Clinicians should also consider the pharmacokinetic and pharmacodynamic properties of medications, including when and how to initiate deprescribing, the researchers add. These considerations are critically important to the clinician‐family‐patient relationship.

The Brown University Child and Adolescent Behavior LetterVol. 42(6)
Good health and well-being
Openalex Percentile: Top 7%
Treatment of Major Depression
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Researchers urge slow tapers in deprescribing — Alison Knopf · The Brown University Child and Adolescent Behavior Letter (2026) | TGRS Research Map | TGRS