Fungal Keratitis Caused by Aureobasidium pullulans: A Case Report

Aureobasidium pullulans is a dematiaceous fungus and a rare causative agent of fungal keratitis. We report a case of Aureobasidium pullulans keratitis that did not respond to conventional therapy despite two months of treatment for a corneal ulcer. A 52-year-old male patient presented with complaints of pain and redness of the right eye (OD) for two months. There was no history of any ocular trauma or surgery, or any other significant ocular and systemic illness. In the left eye (OS), a laser peripheral iridotomy was done 15 days ago. The patient was under treatment for a OD fungal corneal ulcer without any significant improvement after two months. Fungal culture isolated Aureobasidium pullulans as the causative infectious organism. The patient was treated successfully with topical natamycin and systemic itraconazole.

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Publication Details

Journal
Cureus
Published
2026-05-12
DOI
https://doi.org/10.7759/cureus.108733
Primary Topic
Polysaccharides Composition and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Fungal Keratitis Caused by Aureobasidium pullulans: A Case Report

Suwarna Suman, Arushi Kumar
Cureus
Polysaccharides Composition and Applications
article

Fungal Keratitis Caused by Aureobasidium pullulans: A Case Report

Suwarna Suman, Arushi Kumar
article en

Abstract

Aureobasidium pullulans is a dematiaceous fungus and a rare causative agent of fungal keratitis. We report a case of Aureobasidium pullulans keratitis that did not respond to conventional therapy despite two months of treatment for a corneal ulcer. A 52-year-old male patient presented with complaints of pain and redness of the right eye (OD) for two months. There was no history of any ocular trauma or surgery, or any other significant ocular and systemic illness. In the left eye (OS), a laser peripheral iridotomy was done 15 days ago. The patient was under treatment for a OD fungal corneal ulcer without any significant improvement after two months. Fungal culture isolated Aureobasidium pullulans as the causative infectious organism. The patient was treated successfully with topical natamycin and systemic itraconazole.

Cureus
Openalex Percentile: Top 6%
Polysaccharides Composition and Applications
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