Comparing Phenotypic Susceptibility Profiles of Neisseria gonorrhoeae for Tetracycline and Doxycycline

Among 64 Neisseria gonorrhoeae isolates, the MIC50 of tetracycline was 1 µg/mL while the MIC90 was 16 µg/mL. The MIC50 of doxycycline was 1 µg/mL while the MIC90 was 8 µg/mL. The essential agreement between doxycycline and tetracycline was 92.2% (95% CI 82.7-97.4%).

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Publication Details

Journal
Sexually Transmitted Diseases
Published
2026-05-11
DOI
https://doi.org/10.1097/olq.0000000000002321
Primary Topic
Reproductive tract infections research
Type
article
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article

Comparing Phenotypic Susceptibility Profiles of Neisseria gonorrhoeae for Tetracycline and Doxycycline

Lu Liu, Shivani Pasricha, John A. Branda, Francesca Azzato et al.
Sexually Transmitted Diseases
Reproductive tract infections research
article

Comparing Phenotypic Susceptibility Profiles of Neisseria gonorrhoeae for Tetracycline and Doxycycline

Lu Liu, Shivani Pasricha, John A. Branda, Francesca Azzato, Lao-Tzu Allan-Blitz, Jeffrey D. Klausner, Ellen N. Kersh
article en

Abstract

Among 64 Neisseria gonorrhoeae isolates, the MIC50 of tetracycline was 1 µg/mL while the MIC90 was 16 µg/mL. The MIC50 of doxycycline was 1 µg/mL while the MIC90 was 8 µg/mL. The essential agreement between doxycycline and tetracycline was 92.2% (95% CI 82.7-97.4%).

Sexually Transmitted Diseases
University of Southern California (US), Brigham and Women's Hospital (US), The Royal Melbourne Hospital (AU), Harvard University (US), University of California, Los Angeles (US), Massachusetts General Hospital (US), Victorian Infectious Diseases Reference Laboratory (AU), Peter Doherty Institute (AU), Georgia Department of Public Health (US)
Openalex Percentile: Top 7%
Reproductive tract infections research
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