Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures

Fluoroscopy has traditionally been the mainstay imaging technique for guidance during electrophysiology (EP) ablation procedures. The numerous disadvantages associated with radiation exposure for both operators and patients have created the need for zero-fluoroscopy (ZF) approaches. Today, electrophysiologists have access to a wide range of ZF tools, including electroanatomic mapping systems, transoesophageal and intracardiac echocardiography, visualisable sheaths, contact-force sensing catheters, preprocedural advanced cardiac imaging integration, and real-time cardiac magnetic resonance EP guidance. An increasing body of evidence supports the adoption of ZF protocols in managing of the full spectrum of arrhythmias, with feasibility demonstrated without compromise to efficacy or safety. The future of ZF appears highly promising, driven not only by continued refinement of the existing systems but also by the seamless convergence of emerging technologies.

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Publication Details

Journal
Pacing and Clinical Electrophysiology
Published
2026-05-12
DOI
https://doi.org/10.1111/pace.70290
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
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article

Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures

Dimitrios Kotzadamis, Vaios Schismenos, Antonios Antoniadis, Prokopios Mamolis et al.
Pacing and Clinical Electrophysiology
Cardiac Arrhythmias and Treatments
article

Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures

Dimitrios Kotzadamis, Vaios Schismenos, Antonios Antoniadis, Prokopios Mamolis, Vassilios Vassilikos, Alexandros Evangeliou, Georgios Giannopoulos
article en

Abstract

Fluoroscopy has traditionally been the mainstay imaging technique for guidance during electrophysiology (EP) ablation procedures. The numerous disadvantages associated with radiation exposure for both operators and patients have created the need for zero-fluoroscopy (ZF) approaches. Today, electrophysiologists have access to a wide range of ZF tools, including electroanatomic mapping systems, transoesophageal and intracardiac echocardiography, visualisable sheaths, contact-force sensing catheters, preprocedural advanced cardiac imaging integration, and real-time cardiac magnetic resonance EP guidance. An increasing body of evidence supports the adoption of ZF protocols in managing of the full spectrum of arrhythmias, with feasibility demonstrated without compromise to efficacy or safety. The future of ZF appears highly promising, driven not only by continued refinement of the existing systems but also by the seamless convergence of emerging technologies.

Pacing and Clinical Electrophysiology
Hippocration General Hospital (GR)
Industry, innovation and infrastructure
Openalex Percentile: Top 6%
Cardiac Arrhythmias and Treatments
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Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures — Dimitrios Kotzadamis, Vaios Schismenos, et al. · Pacing and Clinical Electrophysiology (2026) | TGRS Research Map | TGRS