A Cross‐Sectional Survey Study Assessing the Quality of Life and Sleep in Spanish Psoriasis Patients
ABSTRACT Background Psoriasis significantly impacts quality of life (QOL) and quality of sleep (QOS) of patients, yet dermatology assessments often do not evaluate sleep. Objectives This cross‐sectional survey study investigates the prevalence of poor QOS, and correlation with QOL in psoriasis patients from Sevilla, Spain. Methods Psoriasis patients completed: Short‐form health survey (SF‐36), Pittsburg sleep quality index (PSQI), Dermatology Life Quality Index (DLQI), and physician‐assessed Psoriasis Area and Severity Index (PASI). The survey response rate was 96.15% (100/104). Statistical analysis employed Pearson's correlations, Mann–Whitney U , and Kruskal–Wallis tests. Results Among the 100 patients (avg age = 49; 52 males), 90% exhibited poor QOS (PSQI > 5), with avg PSQI = 10.34 ± 4.45/21, indicating very poor QOS. The SF‐36 average was 59.57 ± 22.82/100, indicating a nearly normalized average QOL. The average DLQI score was 5.25 ± 5.7/30 indicating a small‐to‐moderate effect on dermatologic QOL, and the average PASI was 2.55 ± 3.51/72 indicating mild disease severity. PSQI negatively correlated with SF‐36 (−0.670, p < 0.001). DLQI positively correlated with PSQI (0.245, p = 0.025) and PASI (0.431, p < 0.001), and negatively with SF‐36 (−0.294, p = 0.003). Worse QOS measured by PSQI correlated with female gender (12.13 ± 8.90 vs. males 8.90 ± 3.75, p < 0.001), use of medications to sleep ( n = 26, p < 0.001), biological treatment ( n = 59, 11.14 ± 4.13 vs. 9.40 ± 4.75, p = 0.045), unemployed status ( n = 40, p < 0.001), and suspected psoriatic arthritis ( n = 17, p = 0.038). Worse QOL measured by SF‐36 also correlated with female gender (50.36 ± 21.12 vs. males 68.48 ± 20.97, p < 0.001), use of medications to sleep ( n = 26, p < 0.001), and unemployed status ( n = 40, p < 0.001). For PSQI, sleep duration was most affected, and medication for sleep was least affected. For SF‐36, vitality/fatigue was most affected, and physical function was least affected. Conclusions Psoriasis patients commonly experience poor QOS, impacting QOL. Particularly women, unemployed patients, and those that use medication to sleep were most affected. Sleep duration and vitality/fatigue represent areas for intervention.
Authors
- Amalia Pérez‐Gil (ORCID: https://orcid.org/0000-0002-6677-2412)
- Lilia Correa-Selm
- Raquel Hernández Sánchez
- Gabriela Piñero-Crespo (ORCID: https://orcid.org/0009-0005-4634-7645)
- María Isabel del Pino Rincón
Institutions
- University of South Florida (US)
- Hospital Universitario de Valme (ES)
Publication Details
- Journal
- JEADV Clinical Practice
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1002/jvc2.70338
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00