A Systematic Topological Picture of ROS Scavenging Activity via Formal Hydrogen Atom Transfer in Phenols and Polyphenols
values that permit deprotonation under physiological conditions. Finally, all the identified criteria for selecting effective polyphenolic antioxidants are validated in real systems, such as anthocyanidins, providing insightful tools for drug design.
Authors
- Laura Orian (ORCID: https://orcid.org/0000-0002-1673-5111)
- Andrea Madabeni
- Davide Zeppilli (ORCID: https://orcid.org/0000-0003-0961-0764)
- Matteo Filippi
Institutions
- University of Padua (IT)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1021/acs.joc.6c00415
- Primary Topic
- Free Radicals and Antioxidants
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Padova