Phytocannabinoids as epigenetic regulators: bridging DNA methylation and redox homeostasis in glioblastoma

C and 8-oxo-dG contents. These results show that cannabinoids alone or in combination with the current standard glioblastoma chemotherapeutic, TMZ, inhibit the progression of GBM and could be used for its clinical treatment. The mechanism of cannabinoids' actions on glioblastoma cells is also proposed.

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Publication Details

Journal
Journal of Applied Genetics
Published
2026-05-12
DOI
https://doi.org/10.1007/s13353-026-01070-x
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Phytocannabinoids as epigenetic regulators: bridging DNA methylation and redox homeostasis in glioblastoma

Anna‐Maria Barciszewska, M Z Naskret-Barciszewska, Małgorzata Giel-Pietraszuk, Agnieszka Belter et al.
Journal of Applied Genetics
Cannabis and Cannabinoid Research
article

Phytocannabinoids as epigenetic regulators: bridging DNA methylation and redox homeostasis in glioblastoma

Anna‐Maria Barciszewska, M Z Naskret-Barciszewska, Małgorzata Giel-Pietraszuk, Agnieszka Belter, Jakub F. Barciszewski, Iwona Gawrońska, L Bartkowski
article en

Abstract

C and 8-oxo-dG contents. These results show that cannabinoids alone or in combination with the current standard glioblastoma chemotherapeutic, TMZ, inhibit the progression of GBM and could be used for its clinical treatment. The mechanism of cannabinoids' actions on glioblastoma cells is also proposed.

Journal of Applied Genetics
Poznan University of Medical Sciences (PL), Institute of Natural Fibres and Medicinal Plants (PL), Institute of Bioorganic Chemistry, Polish Academy of Sciences (PL), University Hospital of Lord’s Transfiguration (PL)
Narodowe Centrum Nauki
Openalex Percentile: Top 7%
Cannabis and Cannabinoid Research
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