Biophysical and biological evaluation of free and liposomal doxorubicin and β-carotene reveals enhanced therapeutic selectivity in MCF-7 breast cancer cells

≈ 20 µg/mL). Overall, these findings suggest that liposomal co-delivery of β-carotene and doxorubicin may enhance therapeutic efficacy while potentially reducing off-target toxicity.

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Publication Details

Journal
Journal of Liposome Research
Published
2026-05-12
DOI
https://doi.org/10.1080/08982104.2026.2671264
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

Biophysical and biological evaluation of free and liposomal doxorubicin and β-carotene reveals enhanced therapeutic selectivity in MCF-7 breast cancer cells

M G.Ibrahim, Hany Elrahman, Ayman M. Ibrahim, Mahmoud A. Elbaset et al.
Journal of Liposome Research
Nanoparticle-Based Drug Delivery
article

Biophysical and biological evaluation of free and liposomal doxorubicin and β-carotene reveals enhanced therapeutic selectivity in MCF-7 breast cancer cells

M G.Ibrahim, Hany Elrahman, Ayman M. Ibrahim, Mahmoud A. Elbaset, Medhat W. Shafaa, Michael Masoomi
article en

Abstract

≈ 20 µg/mL). Overall, these findings suggest that liposomal co-delivery of β-carotene and doxorubicin may enhance therapeutic efficacy while potentially reducing off-target toxicity.

Journal of Liposome Research
Benha University (EG), Portsmouth Regional Hospital (US), University of Portsmouth (GB), Helwan University (EG)
Good health and well-being
Openalex Percentile: Top 9%
Nanoparticle-Based Drug Delivery
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