Threshold‐Gated DNA Nanocages Enable Programmable Quorum‐Like Sensing in Vesicle Communities
generated by a GOX-CAT positive-feedback circuit as the autoinducer, we achieved density-dependent signal accumulation and threshold-triggered reversible structural switching, thereby exhibiting key operational features of quorum-like sensing in vesicle-based communities. This platform provides a general model for studying community organization and cooperative behaviors, with potential applications in biomimetic sensing, programmable smart materials, and stimulus-responsive delivery systems.
Authors
- Pengyan Hao (ORCID: https://orcid.org/0009-0008-4867-6524)
- Yongxi Zhao (ORCID: https://orcid.org/0000-0002-1796-7651)
- Na Wu (ORCID: https://orcid.org/0000-0003-0082-4969)
- Di Lu (ORCID: https://orcid.org/0009-0009-1990-891X)
- Xiaoya Sun
Institutions
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Small
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1002/smll.73751
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China