Ligand-Modulated Cobalt-Catalyzed Alkene Carbocarbonylation Unlocks Aliphatic Ketone Synthesis
, and their derivatives as the electrophiles, thus affording modular access to structurally diverse aliphatic ketones, which might find potential applications in synthetic and medicinal chemistry. Moreover, this protocol is also distinguished by its simple operation, excellent functional group compatibility, and high regio- and chemoselectivity.
Authors
- Shulei Ge
- Zhili Cui
- Changrui Nie
- Jixin Wang
- Lin He (ORCID: https://orcid.org/0000-0001-7437-1443)
- Liangjie Ruan
- Jie Li (ORCID: https://orcid.org/0000-0002-6912-3346)
- Ting Zeng
Institutions
- Chinese Academy of Sciences (CN)
- Lanzhou Institute of Chemical Physics (CN)
- Ministry of Education (KR)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1021/jacs.6c06343
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province
- Science and Technology Program of Suzhou