Understanding regression models in clinical research

Medical research often employs regression models. However, many clinicians are not confident in their ability to interpret these studies, which can lead to misinterpretation and negatively affect clinical practice. This article aims to provide a basic framework for understanding regression models in clinical research. In this article, we explain what regression models are, the purposes they serve, and some of the most common regression models, with examples illustrating how to interpret them in plain language. We discuss common errors and shortcomings in regression models.