Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer
and image large‑scale irregular regions and minute areas down to 100 µm. In ex vivo experiments on porcine gastric tissue, the penetration depth achieved 4 mm, with SNRs exceeding 13 dB and contrast values all greater than 0.5. In vivo experiments enabled targeted imaging of lesions in nude mice. Furthermore, a wireless-powered, magnetically controlled device ensures continuous energy and precise motion for NIR‑II FICE. To our knowledge, this is the first CE platform for NIR-II fluorescence imaging, advancing non-invasive gastrointestinal disease diagnosis/treatment and clinical research.
Authors
- Jinlei Jiang (ORCID: https://orcid.org/0000-0003-4034-7490)
- Shengsheng Cui (ORCID: https://orcid.org/0000-0002-9341-1567)
- Qirui Zhao
- Liu S (ORCID: https://orcid.org/0009-0003-6570-2812)
- Wei Wang (ORCID: https://orcid.org/0000-0002-1293-9168)
- Xi Chen
- Weicheng Wang
- Cheng Zhou
- Zhengting Wang (ORCID: https://orcid.org/0000-0001-5533-5711)
- Daxiang Cui
- Xinyuan Cui
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Advanced Science
- Published
- 2026-05-12
- DOI
- https://doi.org/10.1002/advs.75532
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shanghai
- National Key Research and Development Program of China