Outcomes of endolymphatic sac surgery for lermoyez syndrome: a 2-year and 10-year follow-up

BACKGROUND: Lermoyez syndrome (LS) is a rare auditory disorder, and its treatment is empirical. The efficacy of endolymphatic sac surgery for LS remains unknown. OBJECTIVES: To assess short- and long-term outcomes of endolymphatic sac surgery (ELS) in Lermoyez syndrome (LS). MATERIAL AND METHODS: Retrospective analysis of 19 patients with refractory LS from a tertiary hospital in China. The primary outcome was change in vertigo attack frequency over 6 months at 2- and 10-year follow-ups compared with the 6 months preoperatively. Hearing outcomes and predictors of improvement were evaluated. RESULTS: = 0.029). All patients tolerated endolymphatic sac surgery well. CONCLUSIONS AND SIGNIFICANCE: ELS is a safe, effective option for refractory LS, providing durable vertigo control and helping prevent further hearing deterioration. Efficacy diminishes with advancing stage, supporting earlier surgical intervention to maximize hearing preservation.

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Publication Details

Journal
Acta Oto-Laryngologica
Published
2026-05-12
DOI
https://doi.org/10.1080/00016489.2026.2667877
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Outcomes of endolymphatic sac surgery for lermoyez syndrome: a 2-year and 10-year follow-up

Jiahua Luo, Yatong Zhang, L Han, Yixu Wang et al.
Acta Oto-Laryngologica
Vestibular and auditory disorders
article

Outcomes of endolymphatic sac surgery for lermoyez syndrome: a 2-year and 10-year follow-up

Jiahua Luo, Yatong Zhang, L Han, Yixu Wang, Lisheng Yu
article en

Abstract

BACKGROUND: Lermoyez syndrome (LS) is a rare auditory disorder, and its treatment is empirical. The efficacy of endolymphatic sac surgery for LS remains unknown. OBJECTIVES: To assess short- and long-term outcomes of endolymphatic sac surgery (ELS) in Lermoyez syndrome (LS). MATERIAL AND METHODS: Retrospective analysis of 19 patients with refractory LS from a tertiary hospital in China. The primary outcome was change in vertigo attack frequency over 6 months at 2- and 10-year follow-ups compared with the 6 months preoperatively. Hearing outcomes and predictors of improvement were evaluated. RESULTS: = 0.029). All patients tolerated endolymphatic sac surgery well. CONCLUSIONS AND SIGNIFICANCE: ELS is a safe, effective option for refractory LS, providing durable vertigo control and helping prevent further hearing deterioration. Efficacy diminishes with advancing stage, supporting earlier surgical intervention to maximize hearing preservation.

Acta Oto-Laryngologica
Peking University (CN), Peking University People's Hospital (CN)
National Natural Science Foundation of China, Natural Science Foundation of Beijing Municipality, National Key Research and Development Program of China
Openalex Percentile: Top 6%
Vestibular and auditory disorders
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Outcomes of endolymphatic sac surgery for lermoyez syndrome: a 2-year and 10-year follow-up — Jiahua Luo, Yatong Zhang, et al. · Acta Oto-Laryngologica (2026) | TGRS Research Map | TGRS