The First Case of Linear Cutaneous Lupus Erythematosus Following Covid‐19 Vaccination: A Case Report

ABSTRACT Linear cutaneous discoid lupus erythematosus (LCDLE) is a rare presentation of lupus erythematosus, more frequently observed in children and young adults. Clinically, lesions present as unilateral, linear, erythematous plaques, frequently involving the face, but the neck, trunk, or extremities can also be affected. Several reports have documented cutaneous adverse events following both SARS‐CoV‐2 infection and various types of COVID‐19 vaccination. Among these adverse events, autoimmune skin conditions, such as cutaneous lupus erythematosus, have emerged as an area of interest. Here, we present a challenging case of a 15‐year‐old boy who developed LCDLE on his right upper extremity 1 month after the second dose of COVID‐19 vaccination.

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Journal
Clinical Case Reports
Published
2026-05-01
DOI
https://doi.org/10.1002/ccr3.72703
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
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article

The First Case of Linear Cutaneous Lupus Erythematosus Following Covid‐19 Vaccination: A Case Report

Alireza Ghanadan, Zahra Razavi, Marwa Akhdar, Saman Al‐Zahawi et al.
Clinical Case Reports
SARS-CoV-2 and COVID-19 Research
article

The First Case of Linear Cutaneous Lupus Erythematosus Following Covid‐19 Vaccination: A Case Report

Alireza Ghanadan, Zahra Razavi, Marwa Akhdar, Saman Al‐Zahawi, Fatemeh Saberi, Vahideh Sadat Azhari
article en

Abstract

ABSTRACT Linear cutaneous discoid lupus erythematosus (LCDLE) is a rare presentation of lupus erythematosus, more frequently observed in children and young adults. Clinically, lesions present as unilateral, linear, erythematous plaques, frequently involving the face, but the neck, trunk, or extremities can also be affected. Several reports have documented cutaneous adverse events following both SARS‐CoV‐2 infection and various types of COVID‐19 vaccination. Among these adverse events, autoimmune skin conditions, such as cutaneous lupus erythematosus, have emerged as an area of interest. Here, we present a challenging case of a 15‐year‐old boy who developed LCDLE on his right upper extremity 1 month after the second dose of COVID‐19 vaccination.

Clinical Case ReportsVol. 14(5)
Rafik Hariri University Hospital (LB), Razi Hospital (IR), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 4%
SARS-CoV-2 and COVID-19 Research
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