The emerging role of digital dentistry in managing molar-incisor hypomineralization: A perspective

Molar-incisor hypomineralization (MIH) remains one of the most challenging conditions in pediatric dentistry, with fragile enamel that compromises structural integrity, patient comfort, and the longevity of traditional restorative treatments. The unpredictable bonding to hypomineralized substrates results in frequent restoration failures, reinforcing the need for new approaches. In this opinion piece, we argue that digital dentistry offers promising strategies to improve precision, durability, and patient-centered care in MIH management. Drawing on a clinical case used as a proof of concept to illustrate feasibility, we describe a fully digital workflow including intraoral scanning, CAD/CAM design, and 3D-printed indirect restoration. Digital workflows may also enrich dental education by familiarizing students with emerging technologies. At the same time, we acknowledge key barriers such as cost, accessibility, and the clinician learning associated with digital adoption. Digital solutions hold promise as part of a broader strategy to improve care for patients with MIH.

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Publication Details

Journal
PLOS Digital Health
Published
2026-05-11
DOI
https://doi.org/10.1371/journal.pdig.0001406
Primary Topic
Bone and Dental Protein Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

The emerging role of digital dentistry in managing molar-incisor hypomineralization: A perspective

João Sarmento Pereira Neto, Regina Maria Puppin‐Rontani, Ulysses De Toledo Monteiro, Aline Castilho et al.
PLOS Digital Health
Bone and Dental Protein Studies
article

The emerging role of digital dentistry in managing molar-incisor hypomineralization: A perspective

João Sarmento Pereira Neto, Regina Maria Puppin‐Rontani, Ulysses De Toledo Monteiro, Aline Castilho, Cinthya Jeanette Arias Guillén, Anna Laura Doalto
article en

Abstract

Molar-incisor hypomineralization (MIH) remains one of the most challenging conditions in pediatric dentistry, with fragile enamel that compromises structural integrity, patient comfort, and the longevity of traditional restorative treatments. The unpredictable bonding to hypomineralized substrates results in frequent restoration failures, reinforcing the need for new approaches. In this opinion piece, we argue that digital dentistry offers promising strategies to improve precision, durability, and patient-centered care in MIH management. Drawing on a clinical case used as a proof of concept to illustrate feasibility, we describe a fully digital workflow including intraoral scanning, CAD/CAM design, and 3D-printed indirect restoration. Digital workflows may also enrich dental education by familiarizing students with emerging technologies. At the same time, we acknowledge key barriers such as cost, accessibility, and the clinician learning associated with digital adoption. Digital solutions hold promise as part of a broader strategy to improve care for patients with MIH.

PLOS Digital HealthVol. 5(5)
Universidade Estadual de Campinas (UNICAMP) (BR), Fundação Faculdade de Odontologia (BR), Methodist University of Piracicaba (BR), Indiana University – Purdue University Indianapolis (US)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Openalex Percentile: Top 6%
Bone and Dental Protein Studies
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