Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

ABSTRACT The past half‐century has witnessed developments of major structural biology techniques for protein structure and enzymology, from X‐ray crystallography and NMR to cryo‐electron microscopy (cryo‐EM) and free‐electron laser crystallography (XFEL). Having experienced most of these changes directly in my research, I am reviewing my lifetime research work to highlight synergistic developments in structural biology and enzymology, and provide future perspectives for the emerging new frontier of time‐resolved structural biology.