Skin Problems in Search of Skin Solutions
Effective wound healing depends on timely optimization of the wound environment and appropriate reconstructive strategy. Impaired healing, often driven by infection, ischemia, or systemic factors, increases the risk of chronic wounds and adverse scarring. This review highlights key principles of wound bed preparation, including assessment, debridement, infection control, and appropriate dressing selection. For wounds that fail to progress with standard care, advanced interventions such as skin grafting and cellular and tissue-based products play a critical role in promoting closure and improving outcomes. A structured, algorithmic approach to wound management is essential to optimize healing and minimize complications.
Authors
- Franklin R. Gergoudis (ORCID: https://orcid.org/0009-0003-9226-0861)
- Jessica Ballou
- Luke S. Jones
- Maria Kalogeromitros
- Emmanuel Giannas
- Vignesh Chennupati
- Emma J. Bellen Nordahl
- Michael Manning
- Francescantonio Pugliese
Institutions
- Philadelphia College of Osteopathic Medicine (US)
- University of Nicosia (CY)
- East Carolina University (US)
- Vanderbilt University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Annals of Plastic Surgery
- Published
- 2026-05-11
- DOI
- https://doi.org/10.1097/sap.0000000000004769
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00