Asymmetric α‐Alkylation With Activated and Unactivated Electrophiles by a Highly Productive and Recyclable Lewis Acid/Imidazolium Catalyst

2-type pathways is likely, depending on the electronic properties of the electrophile. This new alkylation concept allows for high practicality, combined with broad applicability and might serve as design prototype for future alkylation catalysts.

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Publication Details

Journal
Angewandte Chemie International Edition
Published
2026-05-11
DOI
https://doi.org/10.1002/anie.7069862
Primary Topic
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
Type
article
Field-Weighted Citation Impact
0.00

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article

Asymmetric α‐Alkylation With Activated and Unactivated Electrophiles by a Highly Productive and Recyclable Lewis Acid/Imidazolium Catalyst

Alexander Allgaier, Johanna Haußmann, Johannes Kästner, René Peters et al.
Angewandte Chemie International Edition
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
article

Asymmetric α‐Alkylation With Activated and Unactivated Electrophiles by a Highly Productive and Recyclable Lewis Acid/Imidazolium Catalyst

Alexander Allgaier, Johanna Haußmann, Johannes Kästner, René Peters, Joris van Slageren, Dominik Hornung, Michael Mistele, Wolfgang Frey, Alexander Beck
article en

Abstract

2-type pathways is likely, depending on the electronic properties of the electrophile. This new alkylation concept allows for high practicality, combined with broad applicability and might serve as design prototype for future alkylation catalysts.

Angewandte Chemie International Edition
University of Stuttgart (DE)
Fonds der Chemischen Industrie, Deutsche Forschungsgemeinschaft
Openalex Percentile: Top 10%
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
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