Peptide-Immobilized Core–Sheath Architecture Sutures with Enhanced Mechanical Strength and Antimicrobial Activity
. Additionally, this demonstrated favorable cytocompatibility. In infected skin wounds, the suture promoted healing by reducing inflammatory infiltration, stimulating collagen regeneration, and downregulating TNF-α expression. This mechanically strong, biocompatible, and persistently antibacterial suture offers a promising strategy for the prevention of SSIs.
Authors
- X Y Chen
- Yiran Wang
- HongDa Yu
- Ruiying Zhang (ORCID: https://orcid.org/0009-0004-2956-3218)
- Bing Zhang
- Yanchuan Guo (ORCID: https://orcid.org/0000-0002-3777-9164)
- Di Sun
Institutions
- Chinese Academy of Sciences (CN)
- China-Japan Friendship Hospital (CN)
- Integrated Chinese Medicine (China) (HK)
- Technical Institute of Physics and Chemistry (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Biomacromolecules
- Published
- 2026-05-11
- DOI
- https://doi.org/10.1021/acs.biomac.5c01250
- Primary Topic
- Surgical Sutures and Adhesives
- Type
- article
- Field-Weighted Citation Impact
- 0.00