Spatial characterization of skin lesions in discoid and systemic lupus erythematosus
vascular endothelial cells, which presented the spatial characteristics of the lymphoid follicle-like structures in chronic LE skin lesions. Collectively, our findings provide a comprehensive spatial characterization of the cellular components and molecular features within LE skin lesions.
Authors
- Yi Yang (ORCID: https://orcid.org/0000-0002-4091-8532)
- Hongyun Zhao (ORCID: https://orcid.org/0000-0002-1251-3888)
- W Zhou (ORCID: https://orcid.org/0000-0003-3338-4971)
- Hai Long (ORCID: https://orcid.org/0000-0001-8590-1761)
- Haoyuan Yin (ORCID: https://orcid.org/0000-0002-1437-6063)
- Junpu Mei (ORCID: https://orcid.org/0000-0003-4630-0765)
- Qianmei Liu (ORCID: https://orcid.org/0000-0002-6455-303X)
- Meiling Zheng (ORCID: https://orcid.org/0000-0003-3990-6777)
- Jingru Tian (ORCID: https://orcid.org/0000-0001-6944-4556)
- R Y Chen (ORCID: https://orcid.org/0009-0006-9946-966X)
- Yufen Huang (ORCID: https://orcid.org/0000-0001-5939-1091)
- Zhi Hu
- Jiajun Huang
- Ming Zhao
- Zhao Zhang (ORCID: https://orcid.org/0009-0002-9671-9935)
- Yu Lei
- Haijing Wu
- Qianjin Lu (ORCID: https://orcid.org/0000-0002-1504-4896)
- Xiaodong Fang (ORCID: https://orcid.org/0000-0001-7061-3337)
- Bo Zhang
- Wei Shi
Institutions
- BGI Group (China) (CN)
- Central South University (CN)
- George Fox University (US)
- Dalian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Dalian University of Technology (CN)
- Peking Union Medical College Hospital (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- Chinese Academy of Medical Sciences Dermatology Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Xiangya Hospital Central South University (CN)
- University of Chinese Academy of Sciences (CN)
- BGI Research (CN)
Publication Details
- Journal
- Nature Communications
- Published
- 2026-05-11
- DOI
- https://doi.org/10.1038/s41467-026-72720-1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Key Programme
- Major Research Plan