Real‐World Efficacy and Safety of Glofitamab‐Based Salvage Therapy in Chinese Patients With Relapsed or Refractory Aggressive B‐Cell Lymphomas

T-cell expansion (p = 0.02). Overall, glofitamab demonstrated durable efficacy and a manageable safety profile in R/R aggressive B-cell lymphoma, with treatment outcomes closely associated with T-cell functional status, supporting its potential as an effective bridging strategy before CAR-T therapy.

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Publication Details

Journal
American Journal of Hematology
Published
2026-05-10
DOI
https://doi.org/10.1002/ajh.70359
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Real‐World Efficacy and Safety of Glofitamab‐Based Salvage Therapy in Chinese Patients With Relapsed or Refractory Aggressive B‐Cell Lymphomas

Wanying Chen, Kaiyu Sheng, Q R Wang, Xiangping Zong et al.
American Journal of Hematology
CAR-T cell therapy research
article

Real‐World Efficacy and Safety of Glofitamab‐Based Salvage Therapy in Chinese Patients With Relapsed or Refractory Aggressive B‐Cell Lymphomas

Wanying Chen, Kaiyu Sheng, Q R Wang, Xiangping Zong, Yuxing Wang, J Zhou, Tao You, Chenwen Wang, Depei Wu, Jia Chen, Haiwen Huang, Xiao Ma
article en

Abstract

T-cell expansion (p = 0.02). Overall, glofitamab demonstrated durable efficacy and a manageable safety profile in R/R aggressive B-cell lymphoma, with treatment outcomes closely associated with T-cell functional status, supporting its potential as an effective bridging strategy before CAR-T therapy.

American Journal of Hematology
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN), First Affiliated Hospital of Soochow University (CN)
Openalex Percentile: Top 6%
CAR-T cell therapy research
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