Influence of placental lipid transport dysfunction on maternal brain inflammation during pregnancy complications

: Disrupted lipid balance alters microglial activity and increases IL-6 and TNF-α levels, showing that impaired placental transport can trigger neuroinflammation during pregnancy. In high-risk cases, early intervention and targeted therapies may help preserve maternal mental health by addressing placenta-brain immune dysregulation.

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Publication Details

Journal
Archives of Physiology and Biochemistry
Published
2026-05-11
DOI
https://doi.org/10.1080/13813455.2026.2640886
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Influence of placental lipid transport dysfunction on maternal brain inflammation during pregnancy complications

Keer Jin, Xiaona Lin, Mengying Liu
Archives of Physiology and Biochemistry
Neuroinflammation and Neurodegeneration Mechanisms
article

Influence of placental lipid transport dysfunction on maternal brain inflammation during pregnancy complications

Keer Jin, Xiaona Lin, Mengying Liu
article en

Abstract

: Disrupted lipid balance alters microglial activity and increases IL-6 and TNF-α levels, showing that impaired placental transport can trigger neuroinflammation during pregnancy. In high-risk cases, early intervention and targeted therapies may help preserve maternal mental health by addressing placenta-brain immune dysregulation.

Archives of Physiology and Biochemistry
Sir Run Run Shaw Hospital (CN)
Good health and well-being
Openalex Percentile: Top 7%
Neuroinflammation and Neurodegeneration Mechanisms
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