Radioiodinated compound FJR01: a novel P2X7R-targeted SPECT tracer for visualizing glioma-associated microglia/macrophages in a rat glioblastoma model
I]FJR01 is well suited as a probe for competitive binding assays to screen next-generation P2X7R-targeted ligands.
Authors
- Zijian Zhou (ORCID: https://orcid.org/0000-0003-2383-8490)
- Fangfei Hu
- Bin Ji (ORCID: https://orcid.org/0000-0002-9672-6441)
- Xiyan Rui
- Yun Ding (ORCID: https://orcid.org/0000-0002-7242-2013)
- Nailian Zhang
- Chuyi Zhang
- Yanshan Li
- Xinran Zhao
- Chao Cheng
- Shengxuan Sun
Institutions
- Department of Health and Social Care (GB)
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Discovery Centre (CA)
- Tongren Hospital (CN)
- Ministry of Education (KR)
- Changhai Hospital (CN)
- Pharmaceutical Formulations (United States) (US)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- University College London (GB)
Publication Details
- Journal
- Journal of Enzyme Inhibition and Medicinal Chemistry
- Published
- 2026-05-11
- DOI
- https://doi.org/10.1080/14756366.2026.2659995
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China