Florid Cemento-Osseous Dysplasia Complicated By Periapical Inflammation: A Clinical Case Analysis and Systematic Review of Diagnostic Challenges

Florid cemento-osseous dysplasia (FCOD) is a rare fibro-osseous disorder characterized by the replacement of normal bone with fibrous connective tissue and mineralized material. While typically asymptomatic and noninterventional, this case report describes a 56-year-old Chinese female presenting with left mandibular swelling and intermittent dull pain initially diagnosed as acute periapical periodontitis affecting teeth #34 and #35. Comprehensive evaluation of clinical, radiographic, and demographic findings confirmed a secondary infection complicating pre-existing FCOD. Root canal therapy for #34 and #35 yielded favorable outcomes, emphasizing the importance of conservative management in such cases.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2026-05-08
DOI
https://doi.org/10.1097/scs.0000000000012425
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
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article

Florid Cemento-Osseous Dysplasia Complicated By Periapical Inflammation: A Clinical Case Analysis and Systematic Review of Diagnostic Challenges

Lei Jing, Jiantao Xu, Yongli Bi
Journal of Craniofacial Surgery
Bone Tumor Diagnosis and Treatments
article

Florid Cemento-Osseous Dysplasia Complicated By Periapical Inflammation: A Clinical Case Analysis and Systematic Review of Diagnostic Challenges

Lei Jing, Jiantao Xu, Yongli Bi
article en

Abstract

Florid cemento-osseous dysplasia (FCOD) is a rare fibro-osseous disorder characterized by the replacement of normal bone with fibrous connective tissue and mineralized material. While typically asymptomatic and noninterventional, this case report describes a 56-year-old Chinese female presenting with left mandibular swelling and intermittent dull pain initially diagnosed as acute periapical periodontitis affecting teeth #34 and #35. Comprehensive evaluation of clinical, radiographic, and demographic findings confirmed a secondary infection complicating pre-existing FCOD. Root canal therapy for #34 and #35 yielded favorable outcomes, emphasizing the importance of conservative management in such cases.

Journal of Craniofacial Surgery
Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
Good health and well-being
Openalex Percentile: Top 5%
Bone Tumor Diagnosis and Treatments
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