Discovery of a Potent Antisarcopenia Drug Molecular Scaffold Derived from <i>Ligusticum chuanxiong</i> and Its Photochemical Synthesis
) provides a compelling lead compound and a novel molecular scaffold for the treatment of sarcopenia.
Authors
- Yongheng Wang (ORCID: https://orcid.org/0000-0002-2372-463X)
- Rong‐Rong He (ORCID: https://orcid.org/0000-0001-5505-5672)
- Y Li
- Qin-Li Wan
- Shuai Zhang (ORCID: https://orcid.org/0000-0002-6099-7696)
- Xin-Luan Wang
- Jian Zou
- Hao Gao
- Yi Ding
- Huan Zhao (ORCID: https://orcid.org/0000-0002-1589-5375)
- Lei Wang
- Xin-Sheng Yao (ORCID: https://orcid.org/0000-0003-1603-4873)
- Qing-Hua Zhou (ORCID: https://orcid.org/0000-0003-0468-9266)
- Chen-Yang He
- Yong-Bin Chen
Institutions
- Translational Research Institute (AU)
- Chinese Academy of Sciences (CN)
- Guangdong Institute for Drug Control (CN)
- Ministry of Education (TH)
- Shenzhen Institutes of Advanced Technology (CN)
- Respiratory and Meningeal Pathogens Research Unit (ZA)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-05-11
- DOI
- https://doi.org/10.1021/jacs.6c01000
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- K. C. Wong Education Foundation
- Fundamental Research Funds for the Central Universities
- National College Students Innovation and Entrepreneurship Training Program
- Basic and Applied Basic Research Foundation of Guangdong Province