The phytochemical analysis of <i>Carissa macrocarpa</i> , cytotoxic potential of fractions, and the molecular modulation on p53 expression in HT-29 and LS174T cell lines
exerts anticancer effects in colorectal cancer cells by modulating p53 and provides a mechanistic rationale for its therapeutic potential.
Authors
- Fatma Alzahraa Mokhtar (ORCID: https://orcid.org/0000-0002-6909-7440)
- Serag Eldin I. Elbehairi (ORCID: https://orcid.org/0000-0003-4680-3215)
- Ahmed Hussein (ORCID: https://orcid.org/0000-0001-5112-7296)
- Ali A. Shati
- Dalia G. El-Kolobby
- Mohammad Y. Alfaifi
- Salma S. Alamri
Institutions
- Modern University for Information and Technology (EG)
- Institute of Pharmacology (CZ)
- University of El Salvador (SV)
- King Khalid University (SA)
Publication Details
- Journal
- Artificial Cells Nanomedicine and Biotechnology
- Published
- 2026-05-11
- DOI
- https://doi.org/10.1080/21691401.2026.2668262
- Primary Topic
- Plant-Derived Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- King Khalid University