Sarcoid Nodular Myopathy Presenting With Hypercalcemia: A Rare Presentation—Case Report

ABSTRACT An 18‐year‐old female patient with no past medical history presented with nonanginal chest pain 2 months after her delivery. She did not report any other symptoms such as cough, dyspnea, nausea, or vomiting. Her vital signs were stable. The only positive finding on physical examination was tenderness and edema, with a palpable lump on her right thigh. Other examinations did not provide any additional information. Her lab results showed elevated calcium (12.5 mg/dL), low parathyroid hormone (5.6 pg/mL), and near‐normal 25‐(OH) Vitamin D levels (27.4 ng/dL). The core needle biopsy of the right thigh muscle revealed patchy lymphocytic infiltration with giant cells, without caseous necrosis, suggestive of sarcoidosis. The patient also had elevated angiotensin‐converting enzyme levels. The computed tomography of the lungs revealed no pulmonary involvement or hilar lymphadenopathy. The patient was treated with 30 mg of prednisolone daily. One month later, her symptoms improved, and calcium levels returned to normal.

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Publication Details

Journal
Clinical Case Reports
Published
2026-05-01
DOI
https://doi.org/10.1002/ccr3.72675
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
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article

Sarcoid Nodular Myopathy Presenting With Hypercalcemia: A Rare Presentation—Case Report

Mahsa Malekian, Sina Hamzehzadeh, Amir Bahrami, Bahareh Mehramuz et al.
Clinical Case Reports
Sarcoidosis and Beryllium Toxicity Research
article

Sarcoid Nodular Myopathy Presenting With Hypercalcemia: A Rare Presentation—Case Report

Mahsa Malekian, Sina Hamzehzadeh, Amir Bahrami, Bahareh Mehramuz, Vahideh Sadra
article en

Abstract

ABSTRACT An 18‐year‐old female patient with no past medical history presented with nonanginal chest pain 2 months after her delivery. She did not report any other symptoms such as cough, dyspnea, nausea, or vomiting. Her vital signs were stable. The only positive finding on physical examination was tenderness and edema, with a palpable lump on her right thigh. Other examinations did not provide any additional information. Her lab results showed elevated calcium (12.5 mg/dL), low parathyroid hormone (5.6 pg/mL), and near‐normal 25‐(OH) Vitamin D levels (27.4 ng/dL). The core needle biopsy of the right thigh muscle revealed patchy lymphocytic infiltration with giant cells, without caseous necrosis, suggestive of sarcoidosis. The patient also had elevated angiotensin‐converting enzyme levels. The computed tomography of the lungs revealed no pulmonary involvement or hilar lymphadenopathy. The patient was treated with 30 mg of prednisolone daily. One month later, her symptoms improved, and calcium levels returned to normal.

Clinical Case ReportsVol. 14(5)
Tabriz University of Medical Sciences (IR)
Gender equality
Openalex Percentile: Top 5%
Sarcoidosis and Beryllium Toxicity Research
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