Optical Biopsy and Diagnosis of Gastric Mucosa-Associated Lymphoid Tissue-Type Lymphoma by Probe-Based Confocal Laser Endomicroscopy

The endoscopic findings of gastric mucosa-associated lymphoid tissue (MALT) lymphoma are highly nonspecific and the sampling error or false-negative probabilities during conventional biopsy make its diagnosis more challenging. Confocal laser endomicroscopy is a novel technology which allows in vivo microscopic analysis of gastrointestinal mucosa. Here we present a case of gastric MALT lymphoma by targeted biopsy guided by magnifying endoscopy and probe-based confocal laser endomicroscopy.

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Publication Details

Journal
Diagnostics
Published
2026-05-10
DOI
https://doi.org/10.3390/diagnostics16101451
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
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article

Optical Biopsy and Diagnosis of Gastric Mucosa-Associated Lymphoid Tissue-Type Lymphoma by Probe-Based Confocal Laser Endomicroscopy

Yunlu Feng, Wen Shi, Xinxin Mao, Mengmeng Zhang et al.
Diagnostics
Esophageal Cancer Research and Treatment
article

Optical Biopsy and Diagnosis of Gastric Mucosa-Associated Lymphoid Tissue-Type Lymphoma by Probe-Based Confocal Laser Endomicroscopy

Yunlu Feng, Wen Shi, Xinxin Mao, Mengmeng Zhang, Xi Wu, Aiming Yang
article en

Abstract

The endoscopic findings of gastric mucosa-associated lymphoid tissue (MALT) lymphoma are highly nonspecific and the sampling error or false-negative probabilities during conventional biopsy make its diagnosis more challenging. Confocal laser endomicroscopy is a novel technology which allows in vivo microscopic analysis of gastrointestinal mucosa. Here we present a case of gastric MALT lymphoma by targeted biopsy guided by magnifying endoscopy and probe-based confocal laser endomicroscopy.

DiagnosticsVol. 16(10)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Openalex Percentile: Top 4%
Esophageal Cancer Research and Treatment
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Optical Biopsy and Diagnosis of Gastric Mucosa-Associated Lymphoid Tissue-Type Lymphoma by Probe-Based Confocal Laser Endomicroscopy — Yunlu Feng, Wen Shi, et al. · Diagnostics (2026) | TGRS Research Map | TGRS