Hemodynamic Modeling and Phase‐Adjustable Reconstruction of Hyperpolarized Cardiac <scp> <sup>13</sup> C MRS </scp> Using <scp> <sup>1</sup> H </scp> Cine and <scp>ECG</scp> Timing
PURPOSE: C]pyruvate and to develop a cardiac phase-adjustable reconstruction framework. METHODS: C MRS. RESULTS: > 0.978), separating LV, RV, and recirculation components and estimating pulmonary transit times consistent with image-based measurements. Retrospective phase correction enabled reconstruction of dynamic HP pyruvate timecourses aligned to specific cardiac phases. CONCLUSION: We present a volume-guided hemodynamic modeling and reconstruction framework that corrects cardiac phase misalignment. This approach improves quantitative robustness across varying heart rates and is applicable to both ECG-gated and nongated acquisitions.
Authors
- Kelley Derner
- Jae Mo Park (ORCID: https://orcid.org/0000-0002-7404-6971)
- Crystal Harrison (ORCID: https://orcid.org/0000-0002-8884-2805)
- Sung‐Han Lin (ORCID: https://orcid.org/0000-0003-1384-4037)
- Corey Mozingo
- Craig R. Malloy
Institutions
- Southwestern Medical Center (US)
- VA North Texas Health Care System (US)
- Advanced Imaging Research (United States) (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2026-05-10
- DOI
- https://doi.org/10.1002/mrm.70426
- Primary Topic
- Advanced NMR Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00